Pro-Collagen Multi-Peptide Booster

Pro-Collagen Multi-Peptide Booster features peptide technology to target key proteins in skin’s extracellular matrix (think like coils on a mattress) to support collagen and elastin production. These proteins visibly plump & firm the skin to address signs of aging, wrinkles & loss of firmness.

Six cutting-edge repairing pro-collagen peptides take cues from substances found in skin’s deeper dermal-epidermal junction to support and visibly improve facial architecture. Hydrating hyaluronic acid and strengthening amino acids further firm, plump + smooth skin in as little as 15 minutes.

Apply Pro-Collagen Multi-Peptide Booster once or twice daily to face, eye area and neck after cleansing, toning and exfoliating. Dispense a pearl-sized amount alone or add to your favorite serum or non-SPF moisturizer. For daytime, follow with SPF 30+.

Key Ingredients: Tridecapeptide-1, Palmitoyl Tetrapeptide-72 Amide, Sh-Polypeptide-121, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine , Polyglucuronic Acid, Glyceryl Glucoside

All Ingredients: Water (Solvent | Good), Glycerin (Humectant, Texture Enhancer, Solvent | Best), Pentylene Glycol (Humectant, Solvent, Preservative | Good), Hydrolyzed Yeast Extract (Antioxidant, Humectant | Best), Pyrus Malus (Apple) Fruit Extract (Antioxidant, Plant Extracts, Humectant | Best), Dimethicone (Silicone, Emollient | Best), Propanediol (Solvent, Texture Enhancer | Good), 1, 2-Hexanediol (Preservative, Humectant, Solvent, Texture Enhancer | Good), Glyceryl Glucoside (Antioxidant, Humectant | Best), Palmitoyl Tetrapeptide-72 Amide (Peptides | Best), Sh-Polypeptide-121 (Peptides | Best), Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine (Peptides | Best), Palmitoyl Tripeptide-5 (Peptides | Best), Tridecapeptide-1 (Peptides | Best), Tetradecyl Aminobutyroylvalylaminobutyric Urea Acetate (Peptides | Best), Polyglucuronic Acid (Film-Forming Agent, Humectant | Good), Sodium Hyaluronate (Humectant, Antioxidant | Best), C9-12 Alkane (Solvent | Good), Ammonium Polyacryloyldimethyl Taurate (Texture Enhancer, Emulsifier | Good), Polygonum Bistorta Root Extract (Antioxidant, Plant Extracts | Best), Bacillus Ferment (Humectant, Peptides, Prebiotic/Probiotic/Postbiotic | Best), Lecithin (Emollient, Emulsifier, Cleansing Agent | Best), Sodium Phytate (Chelating Agent | Good), Coco-Caprylate/Caprate (Emollient | Good), Hexylene Glycol (Solvent, Texture Enhancer | Good), Cetyl Hydroxyethylcellulose (Texture Enhancer, Emollient | Good), Xanthan Gum (Texture Enhancer, Cleansing Agent, Emulsifier | Good), Ethylhexylglycerin (Preservative, Humectant | Good), Caprylyl Glycol (Preservative, Plant Extracts | Good), Magnesium Chloride (Texture Enhancer | Good), Citric Acid (pH Adjuster/Stabilizer, Chelating Agent | Good), Potassium Sorbate (Preservative | Good), Sodium Benzoate (Preservative | Good)

Ingredient Spotlight:

• Tridecapeptide-1: Tridecapeptide-1 is a synthetic peptide that has a documented wrinkle-smoothing effect that works within minutes. Helps improve the appearance of wrinkles; Can also visibly improve rough texture; Has benefits immediately and over time
• Palmitoyl Tetrapeptide-72 Amide: A synthetic peptide that acts on numerous supportive elements in skin, helping to maintain a firmer, tighter look and feel. Supports skin’s tensile strength; Encourages supportive elements in skin; Helps skin maintain a youthful bounce
• Sh-Polypeptide-121: This bio-identical single chain peptide plays a role in helping to shore up skin’s underlying support, smoothing wrinkles and improving resilience, among other benefits. Helps improve the look of wrinkles; Aids in boosting skin’s resilience; Soothing properties
• Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine: A synthetic peptide that helps visibly firm skin by supporting key collagens and other proteins that play a role in maintaining skin’s natural architecture. A synthetic peptide that supports key proteins in skin; Promotes a firmer, less lined look; Great synergy with similar signal peptides
• Polyglucuronic Acid: This plant-derived or synthetic ingredient is a humectant and film-forming agent in cosmetics. Plant-derived or synthetic polysaccharide ingredient; Serves as a film-forming agent and has humectant properties; Can smooth skin and prevent dehydration
• Glyceryl Glucoside: Glyceryl glucoside is a humectant that helps support skin’s water balance for proper moisturization. It also has antioxidant properties. Composed of skin-loving glycerin and glucose; A humectant that draws moisture to skin; Ensures balanced hydration + helps prevent dehydration

International Journal of Cosmetic Science, March 2022, pages 232–248
Pharmaceutical Development and Technology, January 2022, pages 108–125
Health Science Reports, June 2021, pages 1–7
Frontiers in Chemistry, October 2020, pages
International Journal of Molecular Sciences, December 2019, pages 1–12
Life Sciences, October 2018, pages 22–33
Cosmetics, March 2018, pages 1–9

What are peptides?

Peptidesare short chains of amino acids that act as building blocks of proteins including collagen, elastin and keratin. Each peptide plays a key role in skin’s texture and strength.

How does the Pro-Collagen Multi-Peptide Booster work?

In their natural form,peptidescan be unstable, so we opted for highly stabilized lab-engineered peptides in our Pro-Collagen Multi-Peptide Booster. These 'synthetic' peptides can penetrate the upper layers of skin and 'activate' areas that help visibly improve tone, hydration, a feeling of suppleness and a smoother surface. Did you know? Synthetic peptides are created as exact copies of protein fragments in skin. They’re more stable on and within skin, remain intact on skin longer and better reach their target areas.

What is the difference between the new Pro-Collagen Multi-Peptide Booster and the original Peptide Booster?

While the original Peptide Booster was a great formula with wonderful benefits, the Pro-Collagen Multi-Peptide Booster features newer, highly specialized peptides that have a more targeted impact on loss of firmness, decreased resilience, wrinkles and skin's foundational architecture for even better results. Both formulas share a similar lightweight gel texture.

How does Pro-Collagen Multi-Peptide Booster work to visually improve lines and wrinkles in just 15 minutes?

A particularly innovative peptide in this formula,tridecapeptide-1, works by interrupting a key step within skin that leads to the formation of expression lines. With this process sidestepped, facial lines and wrinkles begin to smooth out, and skin looks younger and less fatigued.

Does the Pro-Collagen Multi-Peptide Booster replace my other anti-aging ingredients or products?

No. This focused formula complements your otheranti-aging productsby reinforcing and restructuring the surface layers of skin with highly specialized peptides that affect the dermal-epidermal junction. This unique, targeted benefit is something ingredients such as vitamin C, niacinamide and retinol just cannot do; however, each of those ingredients have their own benefits and can be used alongside peptides.

Can I use the Pro-Collagen Multi-Peptide Booster if I have sensitive or rosacea-prone skin?

It’s not a problem to use the Pro-Collagen Multi-Peptide Booster if you have sensitive or rosacea-prone skin. In fact, its fragrance-free formula contains potent skin-soothing and skin-replenishing antioxidants that help calm.

How long will it take to see an improvement in my skin when using the Pro-Collagen Multi-Peptide Booster?

When using the Pro-Collagen Multi-Peptide Booster, you will notice smoother expression lines and wrinkles within 15 minutes with results lasting up to 4 hours. After 4 weeks of consistent use, you will notice a reduction of depth and volume in the appearance of fine lines and wrinkles.

When should I use the Pro-Collagen Multi-Peptide Booster in my skin care routine?

You can apply the Pro-Collagen Multi-Peptide Booster up to twice per day. After cleansing, toning and exfoliating, apply the rest of your serums, treatments and boosters in order from thinnest to thickest texture. Finish with moisturizer as your last step for PM and moisturizer with SPF during the daytime

What is the difference between the Pro-Collagen Multi-Peptide Booster and similar products on the market?

The Pro-Collagen Multi-Peptide Booster includes a blend of distinctive peptides that are not only used at clinically efficacious levels but are combined with key supporting ingredients that revive healthy cellular energy and influence key collagens and other proteins needed to rebuild and preserve youthful skin. Like all Paula’s Choice products, this booster is also free from natural and synthetic fragrance and other irritants, plus it’s packaged stably to preserve ingredient integrity and efficacy. This product takes a top-down signaling approach to restore and maintain skin's structural support system. While some competitor products may contain more peptides in terms of ingredient count, they are likely using levels below the recommended standard (especially if the product's price is below $40).

Does the Pro-Collagen Multi-Peptide Booster have a noticeable scent?

While Paula's Choice products are fragrance-free, each product may have a unique scent due to its ingredients. The scent of the Pro-Collagen Multi-Peptide Booster is primarily from the ingredient tridecapeptide-1, which dissipates quickly after application. The perception of smell can vary greatly between individuals, so what one person notices, another may not notice at all. Many customers find that they quickly get used to the unique scents of Paula's Choice products and that the benefits outweigh any potential drawbacks. Learn more aboutfragrance-free skin care.

Can I use peptides with retinol?

Yes, peptides and retinol can complement each other in an anti-aging routine. Retinol helps improve the look of uneven texture by supporting skin’s natural renewal process, while peptides help support firmer-looking skin and can be a good choice for pairing with more sensitizing actives. Apply the Pro-Collagen Multi-Peptide Booster before or after your retinol product or use peptides in the morning and retinol at night.

Can I use peptides with vitamin C?

Yes, peptides and vitamin C can be used together. Vitamin C provides antioxidant support while peptides support firmer looking skin. If your skin is sensitive, introduce new combinations gradually.

Are peptides better than retinol for anti-aging?

They can both be effective, but they work differently. Retinol has decades of research supporting its benefits, though it can be more irritating for some people. Peptides can help support firmer-looking skin with less risk of visible sensitivity, making them a good option for reactive skin or for those who don’t tolerate retinol well. Many people use both in their routine for optimal results.

Is the Pro-Collagen Multi-Peptide Booster good for oily or acne-prone skin?

Yes, the lightweight gel texture absorbs quickly without clogging pores or feeling heavy. Peptides help strengthen the skin barrier and calm reactivity, which can benefit acne-prone skin. This booster is also a good option if you find retinol too irritating.

Can I use the Pro-Collagen Multi-Peptide Booster with other Paula’s Choice boosters?

Yes, our boosters are formulated to complement each other, so you can layer them to customize your routine. You can layer the Pro-Collagen Multi-Peptide Booster with others like the C15 Super Booster, 10% Niacinamide Booster or Hyaluronic Acid Booster. Apply boosters from thinnest to thickest texture and introduce new combinations gradually if your skin is sensitive.